What is SAMe?

SAMe (S-adenosyl-L-methionine) is a naturally occurring molecule that is taken to help relieve a variety of symptoms. These symptoms include, but are not limited to, joint pain and optimization of the liver function. SAMe is an important natural supplement because over one-third of Americans suffer from chronic joint pain. The most common method of controlling this pain is with aspirin or ibuprofen, which can lead to severe gastric side effects.

Benefits of SAMe

SAMe (known as S-adenosylmethionine) is not an herb or a hormone. It’s a molecule that all living cells, including our own, produce constantly. To understand SAMe you first need to understand methylation and the importance of this process. Methylation is a simple transaction in which one molecule donates a methyl group (four-atom appendage) to a neighboring molecule within our body. SAMe’s methyl group is composed of one carbon and three hydrogen atoms. These transactions have far-reaching effects that affect everything from fetal development to brain function. It regulates the expression of genes, preserves fatty membranes that insulate our cells, and helps regulate various hormones including serotonin, melatonin, dopamine, and adrenaline. Without SAMe there would be no methylation.

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Why take SAMe Supplements?

SAMe (S-adenosylmethionine) is a compound that is produced naturally by our bodies. However, as we age, our SAMe levels decline. This can lead to a variety of health problems, including joint pain, depression, and liver damage. SAMe supplements are a stable, synthetic replication of the compound. They are neither a drug, herb, vitamin, nor hormone. Instead, they are a highly reactive molecule or key cellular nutrient that has almost no side effects. Since its discovery in 1952, SAMe has become increasingly recognized for its role in maintaining good health. Today, it is one of the top-selling dietary supplements in the world.


  • Moisture content is low
  • Ash content is low
  • Synthetic compound does not exceed 50% of S,S-isomer
  • Provides over 75% S,S-isomer SAMe


  • May improve joint function
  • Possible relief of chronic fatigue syndrome
  • Aids in optimization of liver function

Main Competence

  • Available in chemical and tablet form

Uses Dietary Supplement

  • Dietary Supplement
  • Tablets
  • Fine Chemical

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This information on this website is provided for developmental purposes only. This is not a specification, a guarantee of composition, or certificate of analysis. The information contained herein is correct to the best of our knowledge. Recommendations and suggestions contained on this website are made without guarantee or representation as to results. We suggest you evaluate these recommendations prior to use. Our responsibility for claims arising from breach of warranty, negligence, or otherwise is limited to the purchase price of the material.

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