NMN (nicotinamide mononucleotide) is part of the family of nucleotides, organic molecules which are building blocks of RNA and DNA. NMN is made from vitamin B within in the body. NMN is made up of a nitrogenous base, a sugar, and a phosphate group. It is the key component in creating adenine dinucleotide (NADH). In the body NMN converts into NAD+, so as a result the higher the levels of NMN in the body will increase the body’s levels of NAD. NAD is one of the main factors in boosting the body’s metabolism. NMN is absorbed in the gut though either fatty tissues, the small intestine, liver, and pancreas.
NMN is crucial because it increases the activity of sirtuins. Sirtuins are molecules that fight oxidative stress, DNA damage, and cellular aging. It has also been found that higher levels of sirtuin lead to an increase in fertility. Sirtuins are NAD+ dependent, which is why the body’s levels of NMN is important.