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UD2™
What is Vesta’s UD2Collagen™?
- Undenatured Collagen Type II
- Supports Relief of Joint Pain and Inflammation
- Enables Movement and Active Lifestyles
Whatever pursuits fill your day, UD2Collagen™ supplements can fortify your joints and improve mobility. Seize every opportunity in life and thrive.
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News
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Check out the latest research and resources for UD2Collagen™.

Health Benefits
Your ability to move through the day effortlessly hinges on the health of your joints and bones. Cartilage in your joints cushions bones, allowing smooth movement and preventing uncomfortable friction. Maintaining this health ensures you can engage in activities you love without hindrance. Achieve this by staying active, eating well, avoiding injuries, and getting enough rest. Prioritizing joint and bone health means securing your mobility and vitality both now and in the future.
Frequent knee pain affects approximately 25% of adults, limits function and mobility, and impairs quality of life
Pubmed:
Jinks C, Jordan K, Croft P. Measuring the population impact of knee pain and disability with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain. 2002;100:55–64.
Grotle M, Hagen KB, Natvig B, Dahl FA, Kvien TK. Prevalence and Burden of Osteoarthritis: Results from a Population Survey in Norway. Journal of Rheumatology. 2008;35:677–684.
Peat G, McCarney R, Croft P. Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis. 2001;60:91–97.
Felson DT, Zhang Y. An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthritis & Rheumatism. 1998;41:1343–1355.
About Undenatured Collagen
About Undenatured Collagen
Mechanism of Action
Mechanism of Action
1. UD2™ Undenatured Collagen Type II travels through the stomach and intestine and activates immune cells.
2. When activated immune cells recognize type II collagen in joints, the immune cells stimulate cartilage rebuilding and joint repair.
The Genesis of UD2Collagen™
UD2Collagen™ emerged from a deep-rooted passion for holistic wellness and a relentless pursuit of innovation. Our journey began when a team of dedicated researchers, inspired by the transformative power of natural remedies, embarked on a mission to redefine joint health.
Motivated by personal experiences and a desire to address the limitations of conventional solutions, we delved into the intricate world of collagen. Years of meticulous research, collaboration with experts, and tireless experimentation led us to a breakthrough discovery: the undenatured collagen type 2 formula that would become UD2Collagen™.
Driven by a commitment to excellence and a vision of empowering individuals to live their best lives, we spared no effort in perfecting UD2Collagen™. Rigorous testing, refinement, and validation ensured that every batch met our stringent standards for purity, potency, and efficacy.
Today, UD2Collagen™ stands as a testament to our unwavering dedication to quality, innovation, and the well-being of our community. As we continue to evolve and expand our product offerings, our commitment to excellence remains steadfast, guiding us on a journey of continued discovery and empowerment.
UD2 Works better than Competitor and Analogous Products
UD2 Setting the Standard. Outperforming competitors and analogous products. UD2 offers unparalled functionality and efficiency. Elevate your performance with the UD2-the ultimate solution for superior results.
References
Bagi C.M. Osteoarthritis – Opportunities for nonsurgical therapies. Presented at 8th International Conference of Orthopedic Surgeons and Rheumatology, March 22-23, 2017 Rome, Italy.
Crowley DC, Lau FC, Sharma P, Evans M, Guthrie N, Bagchi M, Bagchi D, Dey DK, Raychaudhuri SP. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci. 2009 Oct 9;6(6):312-21. doi: 10.7150/ijms.6.312. PMID: 19847319; PMCID: PMC2764342.
Di Cesare Mannelli L, Micheli L, Zanardelli M, Ghelardini C. Low dose native type II collagen prevents pain in a rat osteoarthritis model. BMC Musculoskelet Disord. 2013 Aug 1;14:228. doi: 10.1186/1471-2474-14-228. PMID: 23915264; PMCID: PMC3751133.
Felson DT, Zhang Y. An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthritis & Rheumatism. 1998;41:1343–1355.
Grotle M, Hagen KB, Natvig B, Dahl FA, Kvien TK. Prevalence and Burden of Osteoarthritis: Results from a Population Survey in Norway. Journal of Rheumatology. 2008;35:677–684.
Henrotin Y, Chevalier X, Herrero-Beaumont G, McAlindon T, Mobasheri A, Pavelka K, Schön C, Weinans H, Biesalski H; Participants at the Hohenheim Consensus Conference in August 29th 2011. Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities. BMC Res Notes. 2013 Mar 26;6:115. doi: 10.1186/1756-0500-6-115. PMID: 23531101; PMCID: PMC3629992.
Jinks C, Jordan K, Croft P. Measuring the population impact of knee pain and disability with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Pain. 2002 Nov;100(1-2):55-64. doi: 10.1016/s0304-3959(02)00239-7. PMID: 12435459.
Marone PA, Lau FC, Gupta RC, Bagchi M, Bagchi D. Safety and toxicological evaluation of undenatured type II collagen. Toxicol Mech Methods. 2010 May;20(4):175-89. doi: 10.3109/15376511003646440. PMID: 20170336.
Nagler-Anderson C, Bober LA, Robinson ME, Siskind GW, Thorbecke GJ. Suppression of type II collagen-induced arthritis by intragastric administration of soluble type II collagen. Proc Natl Acad Sci U S A. 1986 Oct;83(19):7443-6. doi: 10.1073/pnas.83.19.7443. PMID: 3463976; PMCID: PMC386734.
Peat G, McCarney R, Croft P. Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis. 2001;60:91–97.
Van Vijven JP, Luijsterburg PA, Verhagen AP, van Osch GJ, Kloppenburg M, Bierma-Zeinstra SM. Symptomatic and chondroprotective treatment with collagen derivatives in osteoarthritis: a systematic review. Osteoarthritis Cartilage. 2012 Aug;20(8):809-21. doi: 10.1016/j.joca.2012.04.008. Epub 2012 Apr 17. PMID: 22521757.
Vasiliadis HS, Tsikopoulos K. Glucosamine and chondroitin for the treatment of osteoarthritis. World J Orthop. 2017 Jan 18;8(1):1-11. doi: 10.5312/wjo.v8.i1.1. PMID: 28144573; PMCID: PMC5241539.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. This information on this website is provided for developmental purposes only. This is not a specification, a guarantee of composition, or certificate of analysis. The information contained herein is correct to the best of our knowledge. Recommendations and suggestions contained on this website are made without guarantee or representation as to results. We suggest you evaluate these recommendations prior to use. Our responsibility for claims arising from breach of warranty, negligence, or otherwise is limited to the purchase price of the material.